Esomeprazole – A Drug Update


Esomeprazole is the second most prescribed medication in Australia. It is a proton pump inhibitor prescribed to treat reflux oesophagitis (heartburn), peptic ulcers.

Recent research published in the British Medical Journal BMJ Open, indicates a significant association between the use of proton pump inhibitors and the risk of all cause mortality (death).

This brief module provides an outline of the uses, indications, doses, contraindications, and adverse effects of esomeprazole.

It is recommended for Aboriginal health practitioners, nurses, midwives, doctors, pharmacists, and Aboriginal health workers.

Learning Objectives

At the end of this module participants will be able to:

  • Understand the method of action of esomeprazole.
  • Identify the indications for prescribing esomeprazole.
  • Identify the contraindications and adverse effects of esomeprazole.
  • Broadly identify the risks associated with long-term use.

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